Table 4 Logistic regression analysis of FcγRIIa-H/R131 genotypes in relation to anti-malarial IgG subclasses in the combined study populations

AMA-1

IgG1

H/H

1.15 (0.57–2.31)

0.70

H/R

1

R/R

1.91 (1.00–3.64)

0.05

IgG2

H/H

2.65 (1.43–4.91)

< 0.001

H/R

1

R/R

1.34 (0.69–2.61)

0.38

IgG3

H/H

2.26 (1.21–4.22)

0.01

H/R

1

R/R

1.38 (0.70–2.72)

0.35

IgG4

H/H

2.93 (1.33–6.41)

0.01

H/R

1

R/R

1.15 (0.53–2.48)

0.72

3D7-MSP2

IgG1

H/H

0.10 (0.03–0.20)

< 0.001

H/R

1

R/R

0.86 (0.41–1.80)

0.69

IgG2

H/H

2.76 (1.32–4.47)

< 0.001

H/R

1

R/R

1.27 (0.66–2.46)

0.48

IgG3

H/H

2.37 (1.28–4.38)

0.01

H/R

1

R/R

1.21 (0.62–2.35)

0.58

IgG4

H/H

2.40 (1.29–4.45)

0.01

H/R

1

R/R

1.47 (0.74–2.92)

0.27

FC27-MSP2

IgG1

H/H

1.26 (0.65–2.43)

0.50

H/R

1

R/R

2.38 (1.29–4.39)

0.01

IgG2

H/H

2.37 (1.28–4.38)

0.01

H/R

1

R/R

1.21 (0.62–2.35)

0.58

IgG3

H/H

2.86 (1.50–5.46)

< 0.001

H/R

1

R/R

1.45 (0.70–3.02)

0.32

IgG4

H/H

2.46 (1.33–4.55)

< 0.001

H/R

1

R/R

1.77 (0.66–2.48)

0.47

Pf332-C231

IgG1

H/H

1.33 (0.68–2.59)

0.40

H/R

1

R/R

2.43 (1.31–4.50)

0.01

IgG2

H/H

2.26 (1.21–4.22)

0.01

H/R

1

R/R

1.38 (0.70–2.72)

0.35

IgG3

H/H

2.44 (1.32–4.51)

< 0.001

H/R

1

R/R

1.18 (0.61–2.30)

0.62

IgG4

H/H

1.79 (0.92–3.49)

0.10

H/R

1

R/R

1.33 (0.59–2.97)

0.50