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Table 4 Logistic regression analysis of FcγRIIa-H/R131 genotypes in relation to anti-malarial IgG subclasses in the combined study populations

From: FcγRIIa (CD32) polymorphism and anti-malarial IgG subclass pattern among Fulani and sympatric ethnic groups living in eastern Sudan

Anti-malarial antibodies FcγRIIa-H/R131 genotypes OR (95% CI) p value
AMA-1    
IgG1 H/H 1.15 (0.57–2.31) 0.70
  H/R 1  
  R/R 1.91 (1.00–3.64) 0.05
IgG2 H/H 2.65 (1.43–4.91) < 0.001
  H/R 1  
  R/R 1.34 (0.69–2.61) 0.38
IgG3 H/H 2.26 (1.21–4.22) 0.01
  H/R 1  
  R/R 1.38 (0.70–2.72) 0.35
IgG4 H/H 2.93 (1.33–6.41) 0.01
  H/R 1  
  R/R 1.15 (0.53–2.48) 0.72
3D7-MSP2    
IgG1 H/H 0.10 (0.03–0.20) < 0.001
  H/R 1  
  R/R 0.86 (0.41–1.80) 0.69
IgG2 H/H 2.76 (1.32–4.47) < 0.001
  H/R 1  
  R/R 1.27 (0.66–2.46) 0.48
IgG3 H/H 2.37 (1.28–4.38) 0.01
  H/R 1  
  R/R 1.21 (0.62–2.35) 0.58
IgG4 H/H 2.40 (1.29–4.45) 0.01
  H/R 1  
  R/R 1.47 (0.74–2.92) 0.27
FC27-MSP2    
IgG1 H/H 1.26 (0.65–2.43) 0.50
  H/R 1  
  R/R 2.38 (1.29–4.39) 0.01
IgG2 H/H 2.37 (1.28–4.38) 0.01
  H/R 1  
  R/R 1.21 (0.62–2.35) 0.58
IgG3 H/H 2.86 (1.50–5.46) < 0.001
  H/R 1  
  R/R 1.45 (0.70–3.02) 0.32
IgG4 H/H 2.46 (1.33–4.55) < 0.001
  H/R 1  
  R/R 1.77 (0.66–2.48) 0.47
Pf332-C231    
IgG1 H/H 1.33 (0.68–2.59) 0.40
  H/R 1  
  R/R 2.43 (1.31–4.50) 0.01
IgG2 H/H 2.26 (1.21–4.22) 0.01
  H/R 1  
  R/R 1.38 (0.70–2.72) 0.35
IgG3 H/H 2.44 (1.32–4.51) < 0.001
  H/R 1  
  R/R 1.18 (0.61–2.30) 0.62
IgG4 H/H 1.79 (0.92–3.49) 0.10
  H/R 1  
  R/R 1.33 (0.59–2.97) 0.50