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Table 2 Severe malaria and TLR9 allelic-based association analysis

From: TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression

   The Gambia Malawi
Case-control alleles OR1 95% CI2 p-value3 OR 95% CI p-value3
rs187084 C vs T 0.98 0.82 1.16 0.81 0.82 0.66 1.01 0.06
rs5743836 C vs T 0.92 0.78 1.07 0.26 0.90 0.75 1.08 0.26
rs352139 A vs G 1.08 0.93 1.25 0.33 1.21 1.01 1.45 0.04
rs352140 T vs C 1.03 0.87 1.21 0.77 0.82 0.68 1.00 0.05
Trios          
rs187084 C vs T 0.95 0.82 1.11 0.55 0.91 0.66 1.26 0.56
rs5743836 C vs T 0.95 0.78 1.16 0.62 0.82 0.59 1.16 0.26
rs352139 A vs G 0.92 0.82 1.05 0.22 1.07 0.77 1.49 0.67
rs352140 T vs C 1.00 0.87 1.16 0.97 0.99 0.72 1.36 0.94
  1. 1OR = odds ratio,
  2. 2 CI = confidence interval
  3. 3 for the trios these are TDT p-values