Skip to main content

Advertisement

Table 3 Severe malaria and TLR9 genotype-based association analysis

From: TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression

   The Gambia1 Malawi2
Case-control genotypes OR 95% CI p-value OR 95% CI p-value
rs187084 CT vs TT 0.96 0.75 1.23 0.79 0.82 0.62 1.09 0.17
  CC v TT 0.98 0.57 1.70 0.97 0.60 0.35 1.02 0.06
rs5743836 CT vs TT 0.98 0.74 1.30 0.90 1.01 0.75 1.34 0.95
  CC vs TT 0.81 0.56 1.15 0.25 0.63 0.42 0.97 0.04
rs352139 AG vs GG 1.01 0.77 1.30 0.97 1.22 0.91 1.63 0.17
  AA vs GG 1.22 0.85 1.74 0.27 1.43 0.98 2.07 0.06
rs352140 TC vs CC 0.97 0.76 1.24 0.84 0.77 0.59 1.01 0.06
  TT vs CC 1.36 0.82 2.26 0.22 0.78 0.49 1.25 0.31
  1. 1Adjusted for HbS and ethnicity
  2. 2 Adjusted for HbS