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Table 3 Severe malaria and TLR9 genotype-based association analysis

From: TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression

  

The Gambia1

Malawi2

Case-control

genotypes

OR

95% CI

p-value

OR

95% CI

p-value

rs187084

CT vs TT

0.96

0.75

1.23

0.79

0.82

0.62

1.09

0.17

 

CC v TT

0.98

0.57

1.70

0.97

0.60

0.35

1.02

0.06

rs5743836

CT vs TT

0.98

0.74

1.30

0.90

1.01

0.75

1.34

0.95

 

CC vs TT

0.81

0.56

1.15

0.25

0.63

0.42

0.97

0.04

rs352139

AG vs GG

1.01

0.77

1.30

0.97

1.22

0.91

1.63

0.17

 

AA vs GG

1.22

0.85

1.74

0.27

1.43

0.98

2.07

0.06

rs352140

TC vs CC

0.97

0.76

1.24

0.84

0.77

0.59

1.01

0.06

 

TT vs CC

1.36

0.82

2.26

0.22

0.78

0.49

1.25

0.31

  1. 1Adjusted for HbS and ethnicity
  2. 2 Adjusted for HbS
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Malaria Journal

ISSN: 1475-2875

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