Dynamic range of imaging modalities. Panel A shows the detected band intensities by autoradiography of a serial dilution of genomic DNA detected by the DIG-HTA. Intensities are expressed as the ratio of the sample's intensity divided by the intensity of the highest concentration sample in order to account for inter gel variability. The gels were exposed for 5 minutes (diamonds), 10 minutes (squares) and 15 minutes (triangles). Panel B shows the same dilution series detected by CCD camera at 10 minutes (squares) with the best fit trend line (solid black line). The 5 minute and 15 minute detections are not shown.