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Table 1 Baseline characteristics of patients receiving fixed or loose artesunate and amodiaquine

From: The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum

  AS/AQ AS+AQ p-value
Male: n (%)* 193 (51.5) 212 (56.5) 0.16
Age (months): Mean (SD) 27.5 (14.2) 27.5 (15.2) 0.78
< 12 m n = 54 n = 59  
1–5 y n = 321 n = 316  
Weight (kg): Mean (SD) 10.5 (3.0) n = 373 10.4 (3.1) 0.66
Temp (°C): Mean (SD) 38.4 (0.8) 38.4 (0.9) 0.52
Splenomegaly: n (%) 37 (9.9) 38 (10.1) 0.90
Parasite count (/μL): Median (range) 14.5 (1 – 516.6) 14.2 (1 – 410) 0.78
Haemoglobin (g/dL): Mean (SD) 8.3 (1.7) n = 374 8.2 (1.7) n = 371 0.50
Total WCC (10^9/L): Mean (SD) 11.5 (5.1) n = 337 11.6 (4.8) n = 337 0.42
Platelet count (10^9/L): Mean (SD) 174.4 (112.6) n = 337 183.9 (113.4) n = 338 0.20
AST (IU/L): Mean (SD) 71.0 (71.1) n = 303 70.0 (76.3) n = 298 0.53
ALT (IU/L): Mean (SD) 31.8 (44.9) n = 299 32.0 (53.1) n = 293 0.87
Total bilirubin (μmol/L): Mean (SD) 26.0 (27.8) n = 321 25.7 (33.9) n = 311 0.77
  1. * n = 375 unless stated