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Table 3 PCR-corrected cure rates on all predefined analysis datasets

From: The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum

Data set AS/AQ AS+AQ Difference (95% CI)
AS+AQ – AS/AQ
PP dataset 92.1% (315/342) 92.1% (313/340) 0.0% (-4.0%, 4.1%)
Modified PP dataset 1 95.7% (315/329) 96.0% (313/326) 0.3% (-2.8%, 3.3%)
Full dataset (ITT) 2 85.3% (320/375) 85.9% (322/375) 0.5% (-4.5%, 5.6%)
  1. 1. The modified PP dataset excluded patients vomiting/spitting out study drug in addition to patients already excluded from the PP dataset
  2. 2. Patient withdrawals due to vomiting/spitting out study drug, refusal to take study drug, loss to follow up, patients taking anti-malarial drugs during follow up, etc., were counted as failures for analysis purposes