Skip to main content

Table 3 Haemoglobin concentration, anaemia, and parasitaemia among participants in an antimalarial in vivo efficacy study, Faladje, Mali.

From: Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali

Characteristics AS+AQ AS+SP AQ+SP
Day 0    
   N 133 132 132
   Mean Haemoglobin ± S.D (g/dl) 9.83 ± 1.8 9.71 ± 1.59 9.98 ± 1.59
   Anaemia (< 11 g/dl), n (%) 93 (69.9) 102 (77.3) 97 (73.5)
Day 14    
   N 131 130 130
   §Mean Haemoglobin ± S.D (g/dl) 10.17 ± 1.5 9.89 ± 1.40 10.43 ± 1.49
   *Anaemia (< 11 g/dl), n (%) 87 (65.9) 100 (77.5) 81 (61.4)
Day 28    
   N 105 127 130
   §SMean Haemoglobin ± S.D (g/dl) 10.78 ± 1.49 10.5 ± 1.40 11.05 ± 1.52
   **Anaemia (< 11 g/dl), n (%) 57(54.3) 76 (59.8) 60 (46.2)
Parasitaemia, n (%)    
   Day2 14(10.5) 14(10.7) 67(50.7)
   Day3 2(1.5) 1(0.8) 8 (6.0)
   Day14 5(3.8) 2(1.6) 2(1.5)
   Day28 31(29.5) 9(7.1) 3(2.3)
  1. AS+AQ, artesunate + amodiaquine; AS+SP, artesunate + sulphadoxine-pyrimethamine; AQ+SP, amodiaquine + sulphadoxine-pyrimethamine
  2. *X 2 test: p = 0.014 overall (2 × 3); p = 0.030, AS+SP vs. AS+AQ; p = 0.0046, AS+SP vs. AQ+SP; p = 0.48, AS+AQ vs. AQ+SP.
  3. **X 2 test: p = 0.08 overall (2 × 3); p = 0.027, AQ+SP vs. AS+SP; p = 0.21, AQ+SP vs. AS+AQ; p = 0.39, AS+AQ vs. AS+SP
  4. §Paired t-test comparison day 0 vs. day 14: overall, p < 0.01; AQ+SP, p = 0.001; AS+AQ, p = 0.011; AS+SP, p = 0.033.
  5. §SPaired t-test comparison day 0 vs. day 28: overall, p < 0.001; AQ+SP, p < 0.001; AS+AQ, p < 0.001; AS+SP, p < 0.001
  6. X 2 test: overall (2 × 3); Time points showing difference among the three groups: Day 2, p < 0.001; Day3, p = 0.017; Day 28, p < 0.001.