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Table 3 Efficacy evaluation on Day 28 after PCR correction* Per-Protocol Analysis

From: Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial

Efficacy evaluation AS-SMP
3 days
(N = 435)
AS-SMP
24 hours
(N = 418)
AL
3 days
(N = 392)
ETF – n (%) 0 0 1(0.3%)
LCF – n (%, 95%CI) 3 (0.7%,0.1–2.0) 2 (0.5%,0.1–1.7) 0
LPF – n (%) 0 0 0
ACPR – n (%, 95%CI) 432 (99.3%,98.0–99.9) 416 (99.5%,98.3–99.9) 391 (99.7%,98.6–100.0)
Reinfection rate – (%, 95%CI) 12 (2.8%,1.4–4.8) 13 (3.1%,1.7–5.3) 14 (3.6%,2.0–5.9)
  1. *Subjects for which filters paper were not analyzed or were undetermined result by PCR or protocol violation cases were excluded