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Table 4 Efficacy on D28 after PCR correction by centre (Per-Protocol Analysis)

From: Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial

Efficacy evaluation

AS-SMP

3 days

(N = 435)

AS-SMP

24 hours

(N = 418)

AL

3 days

(N = 392)

Cameroon (n)

85

75

70

ACPR – n (%, 95%CI)

84

(98.8%,93.6–100.0)

74

(98.7,92.8–100.0%)

69

(98.6%,92.3–100.0)

Mali (n)

86

82

85

ACPR – n(%, 95%CI)

86

(100%,95.8–100.0)

82

(100%,95.6–100.0)

85

(100%,95.7–100.0)

Sudan (n)

84

92

73

ACPR – n(%, 95%CI)

84

(100%,95.7–100.0)

92

(100%,96.1–100.0)

73

(100%,95.1–100.0)

Rwanda (n)

180

169

164

ACPR – n(%, 95%CI)

178

(98.9%,96.0–99.9)

168

(99.4%,96.7–100.0)

164

(100%,97.8–100.0)

  1. *Subjects for which filters paper were not analyzed or were undetermined result by PCR or protocol violation cases were excluded