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Table 4 Efficacy on D28 after PCR correction by centre (Per-Protocol Analysis)

From: Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial

Efficacy evaluation AS-SMP
3 days
(N = 435)
AS-SMP
24 hours
(N = 418)
AL
3 days
(N = 392)
Cameroon (n) 85 75 70
ACPR – n (%, 95%CI) 84
(98.8%,93.6–100.0)
74
(98.7,92.8–100.0%)
69
(98.6%,92.3–100.0)
Mali (n) 86 82 85
ACPR – n(%, 95%CI) 86
(100%,95.8–100.0)
82
(100%,95.6–100.0)
85
(100%,95.7–100.0)
Sudan (n) 84 92 73
ACPR – n(%, 95%CI) 84
(100%,95.7–100.0)
92
(100%,96.1–100.0)
73
(100%,95.1–100.0)
Rwanda (n) 180 169 164
ACPR – n(%, 95%CI) 178
(98.9%,96.0–99.9)
168
(99.4%,96.7–100.0)
164
(100%,97.8–100.0)
  1. *Subjects for which filters paper were not analyzed or were undetermined result by PCR or protocol violation cases were excluded