Figure 2

Aligned dot plot showing median and interquartile % functional activity in each complement pathway in children with severe malaria anaemia (cases) and those with uncomplicated malaria (controls). The median functional activity in cases was significantly reduced compared to the controls (9.9% vs 83.4% for CP, 0.09% vs 30.7 for MBL and 36.8% vs 87.7% for AP respectively, P < 0.001). Wilcoxon matched-pairs signed-ranks test was performed with the 36 paired samples.