Genetic diversity and population structure of Plasmodium falciparum in the Philippines

Malaria Journal

Table 3 Observed versus expected heterozygosity in the three P. falciparum populations

Population	No. of loci	IAM			SMM			Mode-shift
		H excess	H deficiency	P	H excess	H deficiency	P
Kalinga	7	6	1	P < 0.05	5	2	NS	NA
Palawan	9	8	1	P < 0.05	3	6	NS	NA
Davao del Norte	10	5	5	NS	4	6	NS	Normal

Proportion of loci with excess or deficiency in observed heterozygosities, relative to expected heterozygosities. Data were subject to mutation drift equilibrium via IAM and SMM, as well as mode-shift analyses. H: heterozygosity. NS: not significant. NA: not applicable. a: sign test, b: Wilcoxon sign-rank test, normal: normal L-shaped distribution = nonbottlenecked population, shifted: shifted mode = bottlenecked population.

ISSN: 1475-2875