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Table 6 Most frequently reported adverse events that occurred at a frequency of >10% in either group of patients enrolled in comparator studies [7, 8, 52]
| Adverse event preferred term | AL n(%) n = 314 | MAS n(%) n = 105 |
|---|---|---|
| Pyrexia | 183 (58.3) | 63 (60.0) |
| Headache | 166 (52.9) | 46 (43.8) |
| Dizziness | 123 (39.2) | 37 (35.2) |
| Anorexia | 108 (34.4) | 37 (35.2) |
| Asthenia | 108 (34.4) | 33 (31.4) |
| Arthralgia | 99 (31.5) | 31 (29.5) |
| Nausea | 82 (26.1) | 34 (32.4) |
| Myalgia | 74 (23.6) | 19 (18.1) |
| Sleep disorder | 70 (22.3) | 30 (28.6) |
| Chills | 67 (21.3) | 20 (19.0) |
| Vomiting | 50 (15.9) | 22 (21.0) |
| Abdominal pain | 61 (19.4) | 20 (19.0) |
| Palpitation | 55 (17.5) | 17 (16.2) |
| Hepatomegaly | 48 (15.3) | 8 (7.6) |
| Splenomegaly | 40 (12.7) | 12 (11.4) |
| Fatigue | 34 (10.8) | 8 (7.6) |
