Figure 4From: The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobsThe interaction of monovalent Fab fragment of PAM 3.10 with VAR2CSA DBL5ε. Association and dissociation of the Fab fragments of PAM 3.10 to a high density of VAR2CSA DBL5ε on the sensor chip surface. The frequency change is shown as a function of time and the black lines show the data from binding experiments with different concentrations of the PAM 3.10 Fab fragment to the surface-bound protein. The red lines show the curve fit for the dissociation phase only. The dissociation rate constant calculated is given on the sensorgram.Back to article page