Figure 2

Vitamin E supplementation reversed α-TTP knockout conferred resistance. (A) Survival rate of α-TTP knockout mice fed with vitamin E supplementary diet (α-ttp^ΔE) and infected with P. berghei NK65 was similar to the C57BL/6J mice fed to a normal diet (B6) or C57BL/6J mice fed to a supplemented diet of vitamin E (B6E). (B) Percentages of parasitaemia of α-TTP knockout mice fed with vitamin E supplementary diet was similar to the C57BL/6J mice. (n = 6) *: p < 0.05 B6, B6E, α-ttp^ΔE vs α-ttp^Δ in panel A. In panel B *: p < 0.01 α-ttp^Δ vs α-ttp^ΔE; ** p < 0.01 α-ttp^Δ vs B6E on day 10 post infection; ***: p < 0.01 α-ttp^Δ vs B6, B6E and α-ttp^ΔE on day 14 post infection.