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Figure 2 | Malaria Journal

Figure 2

From: Alpha-tocopherol transfer protein disruption confers resistance to malarial infection in mice

Figure 2

Vitamin E supplementation reversed α-TTP knockout conferred resistance. (A) Survival rate of α-TTP knockout mice fed with vitamin E supplementary diet (α-ttpΔE) and infected with P. berghei NK65 was similar to the C57BL/6J mice fed to a normal diet (B6) or C57BL/6J mice fed to a supplemented diet of vitamin E (B6E). (B) Percentages of parasitaemia of α-TTP knockout mice fed with vitamin E supplementary diet was similar to the C57BL/6J mice. (n = 6) *: p < 0.05 B6, B6E, α-ttpΔE vs α-ttpΔ in panel A. In panel B *: p < 0.01 α-ttpΔ vs α-ttpΔE; ** p < 0.01 α-ttpΔ vs B6E on day 10 post infection; ***: p < 0.01 α-ttpΔ vs B6, B6E and α-ttpΔE on day 14 post infection.

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