Table 2 In vitro bioassays on P. falciparum CY27 and K1 strains and toxicity assay of the selected plants
From: In vitro and in vivo anti-malarial activity of Boerhavia elegans and Solanum surattense
Scientific name | Artemia salina assay, LC50 (μg/ml) | Anti-plasmodial activity, IC50 (μg/ml) ± SD | SI | ||||
|---|---|---|---|---|---|---|---|
No. | Family | Species | K1 | CY27 | K1 | CY27 | |
1 | Nyctaginaceae | Boerhavia elegans | 1020 | 15.33 ± 0.07 | 11.97 ± 0.05 | 18.19 | 23.3 |
2 | Solanaceae | Solanum surattense | 2507 | 50 ± 0.09 | 40.88 ± 0.84 | 61.32 | 48.86 |
3 | Solanaceae | Solanum alatum | 1050 | >200 | >200 | NA | NA |
4 | Fabaceae | Prosopis juliflora | 1636.68 | 14.78 ± 0.08 | 4.68 ± 0.03 | 110.73 | 349.71 |
5 | Moraceae | Ficus bengalensis | 1050 | >200 | >200 | NA | NA |
6 | Moraceae | Ficus carica | 130.16 | >200 | >200 | NA | NA |
7 | Rutaceae | Citrus limon | 471.39 | >200 | >200 | NA | NA |
8 | Moraceae | Morus alba | 256.42 | >200 | >200 | NA | NA |
9 | Fabaceae | Acacia farnesiana | 460.12 | >200 | >200 | NA | NA |
10 | Rutaceae | Citrus aurantifolia Swingle | 270.17 | >200 | >200 | NA | NA |
Gallic acid | 20 | ND | ND | NA | NA | ||
Controls | Chloroquine | ND | 1.25 ± 0.08 | 0.4 ± 0.01 | NA | NA | |
Artemisinin | ND | 0.002 ± 0008 | 0.007 ± 0.0005 | NA | NA | ||