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Table 4 In vivo activities of plant extracts against P. berghei

From: In vitro and in vivo anti-malarial activity of Boerhavia elegans and Solanum surattense

Plant species

Extract/drug

Dose (mg/kg/day)

Suppression of parasitaemia at day 4 (SP ± SD*)

Survival (%) on day 10

P value (P < 0.05)

S. surattense

Dichloromethane

100

58.11 ± 4.3

80

0.035

Pr. juliflora

Dichloromethane

100

44.13 ± 1.79

100

0.008

 

Water-soluble extract

50

2.59 ± 1.54

100

0.598

B. elegans

Dichloromethane

300

66.18 ± 2.11

100

0.007

 

PBS

-

0

100

 
 

DMSO

18%

0

100

 
 

CQ

25

100

100

 
  1. * SD = Standard deviation