From: Severe Plasmodium vivax malaria exhibits marked inflammatory imbalance
Plasmodium vivax infection | ||||
---|---|---|---|---|
Variables | Non-infected N = 90 | Asymptomatic N = 60 | Mild N = 50 | Severe N = 19 |
Male - no. (%) | 39 (43.3) | 30 (50.0) | 22 (44.0) | 10 (52.6) |
Age - year * | ||||
Median | 38.0 | 42.0 | 33.0 | 22.0 |
Interquartile interval | 25.0 - 51.0 | 32.0 - 48.2 | 26.7 - 48.0 | 16.0 - 35.0 |
Previous malaria episodes * | ||||
Median | 14.0 | 16.0 | 8.0 | 3.5 |
Interquartile interval | 10.0 - 18.0 | 13.0 - 20.0 | 1.0 - 12 | 2.0 - 7.5 |
Years resident in the area * | ||||
Median | 11.4 | 12.5 | 7.4 | 3.0 |
Interquartile interval | 3.2 - 12.8 | 4.2 - 14.6 | 0.5 - 9.2 | 0.5 - 5.4 |
Parasitaemia (parasites/uL) * | ||||
Median | 0 | 73 § | 4,798 | 49,358 |
Interquartile interval | 0 | 54.0 - 85.0 | 2,934 - 7,483 | 32,796 - 54,244 |
Haemoglobin (g/dL) * | ||||
Median | 13.2 | 11.5 | 8.9 | 6.4 |
Interquartile interval | 9.2 - 14.5 | 9.5 - 14.2 | 7.3 - 12.6 | 5.8 - 7.4 |
CRP (ng/mL)* | ||||
Median | 5.65 | 6.6 | 6.5 | 15.3 |
Interquartile interval | 3.7 - 9.47 | 4.12 - 9.35 | 4.9 - 8.7 | 11.9 - 20.65 |
Serum creatinine (mg/dL)* | ||||
Median | 0.85 | 0.9 | 1.1 | 1.7 |
Interquartile interval | 0.7 - 1.2 | 0.7 - 1.2 | 0.7 - 1.3 | 1.42 - 2.45 |
AST (U/L)* | ||||
Median | 41.5 | 50.2 | 95.2 | 385.5 |
Interquartile interval | 32.5 - 68.3 | 38.4 - 73.5 | 42.6 - 251.7 | 277.3 - 487.4 |
UNL | 1.04 | 1.25 | 2.38 | 9.64 |
ALT (U/L)* | ||||
Median | 42.35 | 40 | 58.3 | 238.4 |
Interquartile interval | 37.28 - 53.58 | 23.25 - 65.78 | 43.6 - 87.5 | 105.5 - 364.6 |
UNL | 1.06 | 1 | 1.46 | 4.96 |
Total bilirubin (mg/dL)* | ||||
Median | 0.35 | 0.4 | 0.8 | 2.1 |
Interquartile interval | 0.3 - 0.4 | 0.3 - 0.62 | 0.7 - 2.05 | 1.15 - 3.1 |
Direct bilirubin (mg/dL) | ||||
Median | 0 | 0.11 | 0.3 | 1.1 |
Interquartile interval | 0 - 0 | 0.01 - 0.4 | 0 - 1.63 | 0 - 2.2 |
Indirect bilirubin (mg/dL) | ||||
Median | 0.3 | 0.28 | 0.5 | 1.1 |
Interquartile interval | 0.28 - 0.37 | 0.2 - 0.3 | 0.45 - 0.72 | 0.6 - 1.3 |