|
Duration of gametocyte carriage in days (95% CI)
|
% still gametocytaemic during follow up (n/N)
|
---|
|
Day 14
|
Day 28
|
---|
Kenya, 2003-2004
| | | |
Non-ACT
|
55.6 (28.7-107.7)
|
77.8 (28/36)
|
48.3 (14/29)
|
ACT
|
13.4 (10.2-17.5)
|
55.6 (50/90)
|
11.9 (10/84)
|
p-value
|
< 0.001
|
0.02
|
< 0.001
|
Tanzania, 2006
| | | |
ACT
|
28.6 (17.0-48.0)
|
58.3% (21/36)
|
38.9% (14/36)
|
ACT-PQ
|
6.3 (4.7-8.5)
|
4.9%(2/41)
|
12.2% (5/41)
|
p-value
|
< 0.001
|
< 0.001
|
0.007
|
- All individuals included in the analyses had gametocytes by Pfs25 QT-NASBA at enrolment and were successfully treated, i.e. were free of microscopic asexual parasitaemia between day 3 and the end of follow-up.