Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

Table 2 Sex mixed feeding populations increase mean feeding times

	Exp. 1	Exp. 2
Mosquito feeding population ^b)	Average time ^a) ± SE	Average time ^a) ± SE
1 Infected ^c) + 2 Uninfected Females	11.5 ± 4.3	7.7 ± 1.3
1 Infected + 1 Uninfected Female	8.7 ± 2.9	ND
1 Infected Female + 2 Males	2.4 ± 0.8	5.4 ± 0.8
1 Infected Female + 1 Male	6.2 ± 2.9	ND
1 Uninfected Female	2.4 ± 4.6	5.5 ± 3.2
1 Infected Female	8.7 ± 1.8	8.8 ± 2.4

a) Average feeding time in minutes (i.e, time between start of actual blood meal and retraction of the proboscis, excluding time spent on probing)
b) n = 10 BALB/c mice for each group
c) Infection status of "infected" mosquitoes was confirmed after a successful blood meal

ISSN: 1475-2875