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Table 4 Sporozoite titration for subcutaneous challenge

From: Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

C57BL/6a)

BALB/c

ICR (CD-1)

SPZ

% infected

SPZ

% infected

SPZ

% infected

30

60%

1,000

0%

1,000

0%

100

100%

2,000

0%

3,000

0%

300

100%

3,000

60%

5,000

0%

  

4,000

90%

10,000

80%

  

5,000

90%

15,000

100%

  

8,000

80%

20,000

0%

  

10,000

0%

  
  1. a) N = 5/group for C57BL/6 and ICR (CD-1), N=10/group for BALB/c. Shown is one representative titration experiment. Results were confirmed in independent repeat experiments.