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Table 1 Interpretation of test results

From: Evaluation of a rapid diagnostic test (CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test) for the diagnosis of malaria in a reference setting

For P. falciparum

Test Line(s) visible

Species identification by microscopy corrected by PCR

 

P. falciparum

P. vivax, P. ovale, P. Malariae /no parasites detected

Only HRP-2 or both HRP-2 and pan-pLDH

True positive

Species mismatch*/false positive

No test line or only pan-pLDH

False negative/species mismatch**

True negative

For non- falciparum species

Test Line(s) visible

Species identification by microscopy corrected by PCR

 

P. vivax, P. ovale or P. malariae

P. falciparum /no parasites detected

Only pan-pLDH

True positive

Species mismatch*/false positive

No test line or only HRP-2 or both HRP-2 and pan-pLDH

False negative/species mismatch***

True negative

  1. * Non-falciparum species diagnosed as P. falciparum
  2. ** P. falciparum diagnosed as non-falciparum species
  3. *** Non-falciparum species diagnosed as P. falciparum or as a mixed infection with P. falciparum