Table 6 Sensitivities and specificities of CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test for the detection of non-falciparum species
Results of microscopy corrected by PCR | Numbers | Identified as non-falciparum species by CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test | % Sensitivity (95% C.I.) | % Specificity (95% C.I.) |
|---|---|---|---|---|
All non- falciparum species combined | 175 | 80 | 45.7 (38.2-53.4) | |
P. vivax samples, total | 76 | 59 | 77.6 (66.6-86.4) | |
Parasite density ≤ 500/μl | 25 | 13 | 52.0 (31.3-72.2) | |
Parasite density > 500/μl | 51 | 46 | 90.2 (78.6-96.7) | |
P. ovale samples, total | 76 | 14 | 18.4 (10.5-29.0) | |
Parasite density ≤ 500/μl | 35 | 1 | 2.9 (0.1-14.9) | |
Parasite density > 500/μl | 41 | 13 | 31.7 (18.1-48.1) | |
P. malariae samples, total | 23 | 7 | 30.4 (13.2-52.9) | |
Parasite density ≤ 500/μl | 11 | 1 | 9.1 (0.2-41.3) | |
Parasite density > 500/μl | 12 | 6 | 50.0 (21.1-78.9) | |
P. falciparum and negative samples, total | 415 | 8 | 98.1 (96.2-99.2) | |
P. falciparum | 320 | 8 | 97.5 (95.1-98.9) | |
No parasites seen | 95 | 0 | 100.0 (96.2-100) |