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Table 1 Baseline characteristics of study participants and clinical and parasite response to treatment

From: Monitoring for Plasmodium falciparum drug resistance to artemisinin and artesunate in Binh Phuoc Province, Vietnam: 1998-2009

Characteristics 1998 2001 2004 - 2005 2008 - 2009
Antimalarial drugs 1 ART for 5 days ART for 7 days AS for 7 days AS for 7 days
Source of drugs Vietnam Vietnam China Vietnam
Number of patients 65 69 82 54
Age 22 ± 13 26 ± 13 19 ± 14 30 ± 14
Gender (M/F) 36/29 46/23 61/31 42/12
Temperature (°C) 38.4 ± 1.1 38.6 ± 1.1 38.1 ± 1.2 38.7 ± 1.1
Geometric mean of parasite (Range) 11,200
1,360 - 129,032
13,377
1,120 - 211,200
11,444
1,000 - 200,000
13,942
1,000 - 155,924
Fever Clearance Time (days)
Median
1.4 ± 0.5
1 (1 - 2)
1.7 ± 0.7
2 (1 - 4)
1.4 ± 0.6
1 (1 - 3)
1.4 ± 0.5
1 (1 - 2)
Parasite Clearance time (days)
Median
1.8 ± 0.9
2 (1 - 3)
2.3 ± 0.9
2 (1 - 3)
2.1 ± 0.7
2 (1 - 3)
1.6 ± 0.7
1 (1 - 3)
No. with recurrent parasitaemia (%) 24 (36.9%) 5 (7.2%) 6 (7.3%) 2 (3.7%)
Treatment failure after genotyping 9 (13.8%) 2 (2.9%) 1 (1.2%) 0 (0%)
  1. 1. ART = artemisinin, AS = artesunate