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Figure 4 | Malaria Journal

Figure 4

From: Drug coverage in treatment of malaria and the consequences for resistance evolution - evidence from the use of sulphadoxine/pyrimethamine

Figure 4

Linkage disequilibrium between the dhps A437G + K540E allele and different alleles at dhfr (A) the dhfr triple mutant N51I + C59R + S108N (B) dhfr double mutants C59R + S108N and N51I + S108N (C) the dhfr sensitive allele. The d' values for 2000 + 2001(Kilombero/Ulanga n = 328, Rufiji n = 566) combined and for 2002 (Kilombero/Ulanga n = 381, Rufiji n = 404) are shown. Significant deviation between observed from expected occurred in 2002 indicated by *(p < or = 0.001).

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Malaria Journal

ISSN: 1475-2875

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