| Parascreen | Falcivax | Malascan | First Response | ParaHIT Total |
---|---|---|---|---|---|
Light Microscopy as Gold Standard (Reference) | |||||
Sensitivity | 94.0 | 94.0 | 94.0 | 94.7 | 84.2 |
(95% CI) | (88.52-97.4) | (88.5-97.4) | (88.5-97.4) | (89.5-97.7) | (76.9-90.0) |
Specificity | 72.0 | 72.8 | 69.5 | 69.9 | 80.8 |
(95% CI) | (65.8-77.6) | (66.7-78.3) | (63.2-75.2) | (63.6-75.6) | (75.2-85.6) |
Positive Likelihood Ratio | 3.4 | 3.46 | 3.08 | 3.14 | 4.38 |
(95% CI) | (2.7-4.1) | (2.80-4.27) | (2.53-3.74) | (2.58-3.83) | (3.34-5.73) |
Negative Likelihood Ratio | 0.08 | 0.08 | 0.09 | 0.08 | 0.20 |
(95% CI) | (0.04-0.16) | (0.04-0.16) | (0.04-0.17) | (0.04-0.16) | (0.13-0.29) |
Positive Predictive Value | 65.1 | 65.8 | 63.1 | 63.6 | 70.9 |
(95% CI) | (57.9-71.8) | (58.6-72.5) | (56.0-69.9) | (56.5-70.3) | (63.1-77.8) |
Negative Predictive Value | 95.6 | 95.6 | 95.4 | 96.0 | 90.2 |
(95% CI) | (91.4-98.1) | (91.5-98.1) | (91.1-98.0) | (91.9-98.4) | (85.4-93.8) |
Percentage Agreement (Accuracy) | 79.8 | 80.4 | 78.2 | 78.8 | 82.0 |
Kappa | 0.60 | 0.61 | 0.57 | 0.58 | 0.62 |
PCR as Gold Standard (Reference) | |||||
Sensitivity | 83.6 | 84.8 | 84.8 | 83.6 | 73.7 |
(95% CI) | (77.2-88.8) | (78.5-89.8) | (78.5-89.8) | (77.2-88.8) | (66.4-80.1) |
Specificity | 78.2 | 80.3 | 76.2 | 75.6 | 86.5 |
(95% CI) | (71.7-83.8) | (74.0-85.7) | (69.5-82.0) | (69.0-81.5) | (80.9-91.0) |
Positive Likelihood Ratio | 3.84 | 4.31 | 3.56 | 3.43 | 5.47 |
(95% CI) | (2.92-5.06) | (3.22-5.77) | (2.74-4.61) | (2.65-4.44) | (3.78-7.91) |
Negative Likelihood Ratio | 0.21 | 0.19 | 0.20 | 0.22 | 0.30 |
(95% CI) | (0.15-0.30) | (0.13-0.27) | (0.14-0.29) | (0.15-0.31) | (0.24-0.39) |
Positive Predictive Value | 77.3 | 79.2 | 75.9 | 75.3 | 82.9 |
(95% CI) | (70.62-83.1) | (72.6-84.9) | (69.2-89.8) | (68.5-81.2) | (76.0-88.5) |
Negative Predictive Value | 84.4 | 85.6 | 85.0 | 83.9 | 78.8 |
(95% CI) | (78.2-89.3) | (79.7-90.4) | (78.8-89.9) | (77.6-89.0) | (72.6-84.1) |
Percentage Agreement (Accuracy) | 80.8 | 82.4 | 80.2 | 79.4 | 80.5 |
Kappa | 0.62 | 0.65 | 0.61 | 0.59 | 0.61 |