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Figure 2 | Malaria Journal

Figure 2

From: Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria

Figure 2

Effect of Pg -FET on Hz-induced MMP-9 promoter activity. Hz also induced a 2.5 fold increase of MMP-9 promoter activity, which was completely antagonized (80 and 90% inhibition) by Pg-FET at 50 and 100 μg/ml, respectively. Parthenolide (10 μM) was used as reference inhibitor of MMP-9 (~80% inhibition) promoter activity. Data are expressed as mean ± S.D. of triplicate samples. All experiments were reproduced at least three times. Statistical analyses were performed with GraphPad Prism 5 software, using 1-way ANOVA test followed by Bonferroni's post hoc test. The significance was indicated as *** p < 0.001.

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Malaria Journal

ISSN: 1475-2875

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