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Table 3 Predictors of malaria rapid diagnostic test (RDT) specificity (RDT negative, expert microscopy negative) in Blantyre, Malawi, 2009

From: Comparative field performance and adherence to test results of four malaria rapid diagnostic tests among febrile patients more than five years of age in Blantyre, Malawi

  Specificity n/N(%) Unadjusted odds ratio (P value) Adjusted odd ratio Model 1 (P value) Adjusted odds ratio Model 2 (P value)
RDT type     
   Bioline SD 109/283 (39) 0.5 (< 0.001) 0.5 (< 0.001)  
   First response malaria 128/307 (42) 0.6 (< 0.001) 0.7 (0.01)  
   Paracheck 530/776 (68) 1.8 (< 0.001) 2.1 (< 0.001)  
   ICT diagnostics 311/574 (54) Referent Referent  
Age     
   5 to ≤ 15 yrs 278/680 (41) 0.4 (< 0.001) 0.4 (< 0.001) 0.4 (< 0.001)
   > 15 yrs 778/1211 (64) Referent Referent Referent
Temperature     
   ≥37.5°C 422/790 (53) 0.8 (0.03) 0.8 (0.02) 0.9 (0.20)
   < 37.5°C 640/1092 (59) Referent Referent Referent
Self-treated with antimalarial in past 2 weeks     
   Yes 126/254 (50) 0.7 (0.02) 0.7 (0.05) 0.5 (< 0.001)
   No 920/1605 (57) Referent Referent Referent
RDT performed by:     
   Community health worker 346/810 (43) 0.4 (< 0.001)   0.4 (< 0.001)
   Laboratory technician 732/1130 (65) Referent   Referent
  1. Model 1 assesses RDT type adjusted for patient age, temperature and self-treatment with anti-malarials.
  2. Model 2 assesses RDT test operator (community health worker versus laboratory technician) RDT test operator adjusted for patient age, temperature and self-treatment with anti-malarials.