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Table 3 Predictors of malaria rapid diagnostic test (RDT) specificity (RDT negative, expert microscopy negative) in Blantyre, Malawi, 2009

From: Comparative field performance and adherence to test results of four malaria rapid diagnostic tests among febrile patients more than five years of age in Blantyre, Malawi

 

Specificity

n/N(%)

Unadjusted odds ratio

(P value)

Adjusted odd ratio Model 1

(P value)

Adjusted odds ratio Model 2

(P value)

RDT type

    

   Bioline SD

109/283 (39)

0.5 (< 0.001)

0.5 (< 0.001)

 

   First response malaria

128/307 (42)

0.6 (< 0.001)

0.7 (0.01)

 

   Paracheck

530/776 (68)

1.8 (< 0.001)

2.1 (< 0.001)

 

   ICT diagnostics

311/574 (54)

Referent

Referent

 

Age

    

   5 to ≤ 15 yrs

278/680 (41)

0.4 (< 0.001)

0.4 (< 0.001)

0.4 (< 0.001)

   > 15 yrs

778/1211 (64)

Referent

Referent

Referent

Temperature

    

   ≥37.5°C

422/790 (53)

0.8 (0.03)

0.8 (0.02)

0.9 (0.20)

   < 37.5°C

640/1092 (59)

Referent

Referent

Referent

Self-treated with antimalarial in past 2 weeks

    

   Yes

126/254 (50)

0.7 (0.02)

0.7 (0.05)

0.5 (< 0.001)

   No

920/1605 (57)

Referent

Referent

Referent

RDT performed by:

    

   Community health worker

346/810 (43)

0.4 (< 0.001)

 

0.4 (< 0.001)

   Laboratory technician

732/1130 (65)

Referent

 

Referent

  1. Model 1 assesses RDT type adjusted for patient age, temperature and self-treatment with anti-malarials.
  2. Model 2 assesses RDT test operator (community health worker versus laboratory technician) RDT test operator adjusted for patient age, temperature and self-treatment with anti-malarials.