Skip to main content
Figure 2 | Malaria Journal

Figure 2

From: Prospective strategies to delay the evolution of anti-malarial drug resistance: weighing the uncertainty

Figure 2

The waiting time to appearance. Top) The waiting time to appearance in a treated individual is plotted against the mutation rate for a range of parasite densities. Horizontal lines mark the point where exactly one appearance is expected in treated populations of different size. Bottom) Colors encode categorical descriptions of the time to appearance for parameters that span the relevant range for the number of people treated in one year and the probability of appearance, per treatment. In both panels, the red lines are centered on a mutation rate of 10 -17.2(i.e., two independent mutations at the rate for mutations that confer SP resistance), parasite densities of 10 10, and 1 billion treatment courses per decade. The lines span parasite densities from 10 9to 10 11and global demand from 100 million to 5 billion.

Back to article page