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Table 3 Disease pattern in PbAus-infected C57BL/6Aus mice treated with 2 × 5 mg/kg/d rtemisone.

From: Artemisone effective against murine cerebral malaria

Group Compound Treatment* (days post-inoculation) Disease pattern
    Latency, days Cerebral malaria Anemic malaria Cured**
1 - - 0 5/6 1/6 -
2 DMSO (25 μl) 3-8 0 3/6 3/6 -
3 Artemisone 3-8 10 (n = 1) 0/6 1/6 5/6
4 Artemisone 4-8 11 (n = 1) 0/6 1/6 5/6
5 Artemisone 5-8 10 (n = 4) 0/5 3/5 2/5†,‡
  1. *2 × 5 mg/kg/d every day except day 8 (1 injection, 5 mg/kg/d).
  2. ** No recrudescence
  3. Significant vs. control
  4. Significant vs. other artemisone-treated groups