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Table 4 Disease pattern in PbAus-infected C57BL/6 mice treated with artesunate or artemisone twice a day, on days 7-9 post-inoculation.

From: Artemisone effective against murine cerebral malaria

Compound Dose Infection outcome
   Cerebral malaria Anemic malaria Cured
DMSO 20 μl 4/8 4/8 0/8
Artesunate 2 × 2.5 mg/kg/d 6/8 2/8 0/8
  2 × 5 mg/kg/d 1/8* 7/8* 0/8
Artemisone 2 × 2.5 mg/kg/d 0/8* 3/8 5/8*
  2 × 5 mg/kg/d 0/8* 0/8* 8/8*
  1. *Significant vs. control.
  2. Significant vs. artesunate.