Figure 1

Blood levels of soluble ICAM-1 with increasing severity of malaria. Soluble ICAM-1 concentrations were significantly different among the three groups, p < 0.0001 (Kruskal-Wallis). Levels among fatal cases were significantly higher than among survivors with severe disease, p < 0.00065 (Wilcoxon); and higher in severe disease than among those with uncomplicated malaria, p < 1.27 × 10^-12 (Wilcoxon). Horizontal line is the median, brackets span the 25^th to 75^th percentile.