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Table 1 Clinical characteristics of the patients.

From: Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda

  All patients n = 160 Uncomplicated malaria out-patients (UM), n = 53 Severe malaria survivors (SM-s) n = 80 Fatal malaria (SM-f),* n = 27
Age (years) median (IQR) 2.2 (1.2 - 4.4) 4.4 (2.2 - 8) 1.6 (1 - 3.1) 1.9 (1.2-3.4)
Sex (female:male) 79:81 24:29 37:43 18:9
# of days ill prior to presentation median (IQR) 3 (3-4) 3 (2-4) 3 (3-4) 4 (2-6.5)
Haemoglobin (g/dL) median (IQR) 6.3 (4.2-9.6) 10.1 (9.4 - 11.3) 4.4 (3.4 - 5.6) 5.9 (4.6 - 8.5)
WBC/μL median (IQR) 10,200 (6,800 - 14,300) 7,500 (5,200 - 9,000) 12,150 (9,375 - 16,000) 13,000 (8,500 - 25,125)
Monocytes/μL median (IQR) 66 (39 - 114) 48 (33 - 63) 94 (50 - 137) 83 (51 - 125)
Parasitized red cells/μL median (IQR) 39,600 (11,405-150,830) 37,680 (18,140-115,000) 37,010 (7,500-151,095) 118,920 (24,000-271,350)
# with cerebral malaria 39 0 24 15
# with severe malaria anaemia 54 0 47 7
# with both cerebral malaria and severe malaria anaemia 11 0 9 2
  1. Patients with cerebral malaria or severe malaria anaemia are a subset of those with fatal or severe disease.
  2. * Three patients with fatal malaria did not meet criteria for cerebral malaria or severe malarial anaemia.