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Figure 2 | Malaria Journal

Figure 2

From: Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

Figure 2

AMA1 peptide pools and minimal epitopes elicit ICS CD4+ and CD8+ T cell multifunctional responses. AMA1 peptide pools (P) and associated minimal CD8+ T epitopes (E) were tested in ICS assays using PBMC collected 10 days (v005), 4 months (v001, v002), 7 months (v012) and 10 months (v008) following immunization. Multifunctional activity was measured as % cytokine producing CD4+ and CD8+ T cells producing at least two cytokines among IFN-γ, TNF-α and IL-2.

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