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Table 1 Characteristics of 2050 Ghanaian children at 15 months of age, i.e. six month after the third dose of IPTi-SP
| Parameter | Tamale | Afigya Sekyere | P |
|---|---|---|---|
| No. | 1086 | 964 | |
| Proportion girls (%) | 50.2 | 49.3 | 0.68 |
| Examination for present study (15 months of age) in rainy season (%) | 89.6 | 49.3 | < 0.0001 |
| SP group : placebo group | 542 : 544 | 485 : 479 | 0.86 |
| Current P. falciparum infection | |||
| by microscopy (%; n/n) | 11.0 (119/1084) | 24.3 (229/944) | < 0.0001 |
| GMPD (parasites/μL, 95%CI) | 2312 (1599-3344) | 1455 (1105-1917) | 0.03 |
| by PCR (%) | 23.6 (248/1049) | n.a. | - |
| Current malaria episode (%, n/n) | 7.4 (80/1084) | 11.3 (107/944) | 0.002 |
| Febrile (%, n/n) | 12.8 (138/1082) | 6.1 (59/964) | < 0.0001 |
| History of fever within 48 h (%, n/n) | 31.7 (344/1086) | 31.8 (307/964) | 0.93 |
| Haemoglobin (g/dL; mean, range) | 8.91 (4.7-12.7) | 9.90 (2.0-15.0) | < 0.0001 |
| Proportion anaemic (Hb < 11 g/dL; %, n/n) | 94.0 (1019/1084) | 74.4 (715/961) | < 0.0001 |
| Proportion severely anaemic (Hb < 7 g/dL; %, n/n) | 8.0 (87/1084) | 4.9 (47/961) | 0.004 |
| Proportion with prior episode(s) of malaria (%, n/n) | 47.4 (515/1086) | 57.6 (555/964) | < 0.0001 |
| No. of previous malaria episodes (mean, range) | 0.67 (0-5) | 1.23 (0-7) | < 0.0001 |
