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Table 3 Univariate and multivariate associations with microscopically visible, polyclonal P. falciparum infections

From: Multiplicity of Plasmodium falciparum infection following intermittent preventive treatment in infants

Parameter No. Mean MOI (median, range) P Multivariate analysisa Polyclonal infections (%) OR (95%CI) P Multivariate analysisb
     b SE P     aOR (95%CI P
Previous IPTi-SP
   No 142 2.38 (2, 1-6)      72.5 1   1  
   Yes 135 2.42 (2, 1-5) 0.78 -0.05 0.22 0.82 74.8 1.12 (0.64-1.99) 0.67 0.93 (0.52-1.64) 0.79
Cohort
   Tamale 104 2.57 (2, 1-5)      78.8 1   1  
   Afigya Sekyere 173 2.30 (2, 1-6) 0.07 -0.67 0.26 0.01 70.5 0.64 (0.35-1.18) 0.13 0.53 (0.28-1.03) 0.06
Current malaria episode
   No 114 2.21 (2, 1-6)      64.0 1   1  
   Yes 163 2.53 (2, 1-5) 0.01 0.55 0.24 0.02 80.4 2.30 (1.29-4.11) 0.002 2.35 (1.27-4.32) 0.006
Parasite density (/μL)
   Log10 277 n.a. 0.049 0.24 0.13 0.07 n.a. 1.48 (1.08-2.03) 0.01 1.38 (0.99-1.94) 0.06
Prior malaria episodes
   None 72 2.50 (2, 1-5)      81.9 1   1  
   Any 205 2.37 (2, 1-6) 0.30 -0.19 0.26 0.46 70.7 0.53 (0.26-1.09) 0.06 0.51 (0.25-1.05)c, d 0.07
Season
   Dry season 92 2.49 (2, 1-5)      79.3 1   1  
   Rainy season 185 2.36 (2, 1-6) 0.32 -0.77 0.27 0.004 70.8 1.58 (0.84-3.01) 0.13 0.36 (0.18-0.72) 0.004
  1. a, multivariate results are derived from non-parametric ordinal regression analysis including all listed parameters. b, adjusted odds ratios (aORs) are derived from logistic regression models including all other listed parameters; SE, standard error; OR, odds ratio; 95%CI, 95% confidence interval; n.a., not applicable; c, exchanging with number of previous malaria episodes (0-7): aOR, 0.98, 95%CI, 0.81-1.19; P = 0.84. d, The proportion of polyclonal infections according to arbitrarily set time periods from last previous episode was: <8 weeks (n = 65), 76.9%; 8-16 weeks (n = 62), 72.6%; >16 weeks (n = 78), 64.1%. Exchanging this graded parameter with prior episodes per se yielded respective aORs (95%CIs) of 0.73 (0.30-1.78), 0.72 (0.29-1.76), and 0.32 (0.14-0.73).