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Table 2 dhfr and dhps genotype classification

From: Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations

  dhfr codon   dhps codon
  N51I C59R S108N   A437G K540E
Single X    Single X  
   X     X
    X    
Double X X   Double X X
   X X    
  X   X    
Triple X X X    
  1. Each row represents a mutant genotype for either the dhfr gene or dhps gene. A white box represents a wildtype codon whereas a box with an "X" represents a mutant codon. The MGF database (Additional File 2) reports the frequency of mutant genotypes using the single, double, and triple mutant categories for dhfr and the single and double mutant categories for dhps.