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Table 2 dhfr and dhps genotype classification

From: Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations

 

dhfr codon

 

dhps codon

 

N51I

C59R

S108N

 

A437G

K540E

Single

X

  

Single

X

 
  

X

   

X

   

X

   

Double

X

X

 

Double

X

X

  

X

X

   
 

X

 

X

   

Triple

X

X

X

   
  1. Each row represents a mutant genotype for either the dhfr gene or dhps gene. A white box represents a wildtype codon whereas a box with an "X" represents a mutant codon. The MGF database (Additional File 2) reports the frequency of mutant genotypes using the single, double, and triple mutant categories for dhfr and the single and double mutant categories for dhps.