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Table 3 Genotype frequency calculation rubric

From: Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations

  Mutant Frequency = Wildtype Frequency = Mixed Frequency =
Combined (Mu + Mi)/(Mu + Mi + Wt) Wt/(Mu + Mi + Wt) N/A
Excluded Mu/(Mu + Wt) Wt/(Mu + Wt) N/A
Separate Mu/(Mu + Wt + Mi) Wt/(Mu + Wt + Mi) Mi/(Mu + Wt + Mi)
Split (MAF only) (Mu + Mi)/[Mu + Wt + (2 × Mi)] (Wt + Mi)/[Mu + Wt + (2 × Mi)] N/A
N/A Mi not described.
Mutant frequency reported directly from study
Mi not described.
Wildtype frequency reported directly from study
N/A
  1. Mu = number of isolates carrying pure mutant genotype
  2. Mi = number of isolates carrying mixed mutant genotype
  3. Wt = number of isolates carrying pure wildtype genotype