| Non-P. falciparum | P. falciparum | |
---|---|---|---|
 |  | Uncomplicated | Severe |
 | (n = 26) | (n = 64) | (n = 14) |
Demographics | Â | Â | Â |
Male/female | 20/6 | 51/13 | 6/8 |
Age, years | 40 (17-62) | 40 (11-67) | 40 (26-57) |
Continent of acquisition | Â | Â | Â |
Africa | 12 (46%) | 60 (94%) | 12 (86%) |
Asia | 9 (35%) | 3 (5%) | 1 (7%) |
South America | 5 (19%) | 1 (2%) | 1 (7%) |
Vital signs on admission | Â | Â | Â |
Body temperature, °C | 38.8 (36.1-41.5) | 38.7 (36.1-40.6) | 38.8 (36.8-40.6) |
Pulse rate, beats per minute | 90 (60-130) | 95 (68-120) | 108 (78-140) |
Systolic blood pressure, mm Hg | 123 (100-196) | 120 (95-185) | 118 (80-160) |
Laboratory data on admission | Â | Â | Â |
Parasite load, throphozoites/μl | ND | 5,502 (1.0-385,000) * | 205,600 (80,500-860,000) |
Plasma lactate, mmol/l | 1.4 (0.7-3.0) * | 1.5 (0.5-4.4) * | 2.6 (0.9-5.8) |
Haemoglobin, mmol/l | 8.2 (6.1-10.1) | 8.7 (5.3-11.1) * | 7.6 (3.8-10.2) |
Leucocytes, Ă— 109/l | 5.2 (1.9-9.3) | 5.5 (1.8-11.3) | 6.6 (3.2-18.5) |
Platelets, Ă— 109/l | 93.0 (10.0-205.0) * | 78.5 (16.0-247.0) * | 27.0 (3.0-152.0) |
C-reactive protein, mg/l | 86.5 (18.0-208.0) * | 109.0 (5.0-278.0) * | 190.0 (91.0-265.0) |
Serum creatinine, μmol/l | 94.0 (66.0-149.0) | 103.5 (63.0-208.0) | 102.5 (70.0-199.0) |
Total bilirubin, μmol/l | 24.0 (6.0-84.0) * | 25.0 (7.0-164.0) * | 54.0 (20.0-269.0) |