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Table 1 General characteristics and laboratory results on admission of patients with various species of malaria. Data are given as median (range).

From: Neopterin and procalcitonin are suitable biomarkers for exclusion of severe Plasmodium falciparum disease at the initial clinical assessment of travellers with imported malaria

 

Non-P. falciparum

P. falciparum

  

Uncomplicated

Severe

 

(n = 26)

(n = 64)

(n = 14)

Demographics

   

Male/female

20/6

51/13

6/8

Age, years

40 (17-62)

40 (11-67)

40 (26-57)

Continent of acquisition

   

Africa

12 (46%)

60 (94%)

12 (86%)

Asia

9 (35%)

3 (5%)

1 (7%)

South America

5 (19%)

1 (2%)

1 (7%)

Vital signs on admission

   

Body temperature, °C

38.8 (36.1-41.5)

38.7 (36.1-40.6)

38.8 (36.8-40.6)

Pulse rate, beats per minute

90 (60-130)

95 (68-120)

108 (78-140)

Systolic blood pressure, mm Hg

123 (100-196)

120 (95-185)

118 (80-160)

Laboratory data on admission

   

Parasite load, throphozoites/μl

ND

5,502 (1.0-385,000) *

205,600 (80,500-860,000)

Plasma lactate, mmol/l

1.4 (0.7-3.0) *

1.5 (0.5-4.4) *

2.6 (0.9-5.8)

Haemoglobin, mmol/l

8.2 (6.1-10.1)

8.7 (5.3-11.1) *

7.6 (3.8-10.2)

Leucocytes, Ă— 109/l

5.2 (1.9-9.3)

5.5 (1.8-11.3)

6.6 (3.2-18.5)

Platelets, Ă— 109/l

93.0 (10.0-205.0) *

78.5 (16.0-247.0) *

27.0 (3.0-152.0)

C-reactive protein, mg/l

86.5 (18.0-208.0) *

109.0 (5.0-278.0) *

190.0 (91.0-265.0)

Serum creatinine, μmol/l

94.0 (66.0-149.0)

103.5 (63.0-208.0)

102.5 (70.0-199.0)

Total bilirubin, μmol/l

24.0 (6.0-84.0) *

25.0 (7.0-164.0) *

54.0 (20.0-269.0)

  1. p-values as compared with severe P. falciparum malaria.
  2. * indicates p < 0.01
  3. ND, not done