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Figure 1 | Malaria Journal

Figure 1

From: CPP-ZFN: A potential DNA-targeting anti-malarial drug

Figure 1

CPP-ZFN. A. Plasmodium-targeting peptide having signal peptides for infected RBC penetration, merozoite import, and organelle targeting, conjugated with Plasmodium specific zinc finger nuclease. B. It is hypothesized that the Plasmodium-targeting peptide will cross the membrane barriers of RBC and Plasmodium, and ZFN will introduce a double-strand break in the vital gene of the Plasmodium genome (a, b), leading to loss of gene function (c) and finally parasite death.

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