Skip to main content

Table 1 Distribution of HO-1 promoter genotypes and allele frequencies of the three ethnics (Thai, Burmese, Karen) of malaria patients

From: Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity

 

Ethnic

 

Thai

Burmese

Karen

n

119

240

118

Alleles, n (%)

   

S

132 (55.5%)

236 (49.2%)

133 (56.4%)

M

93 (39.1%)

205 (42.7%)

81 (34.3%)

L

13 (5.5%)

39 (8.1%)

22 (9.3%)

Genotypes, n (%)

   

S/S

39 (32.8%)

57 (23.8%)a

40 (33.9%)

S/M

50 (42.0%)

97 (40.4%)

45 (38.1%)

S/L

4 (3.4%)b

25 (10.4%)

8 (6.8%)

M/M

18 (15.1%)

49 (20.4%)c

12 (10.2%)

M/L

7 (5.9%)

10 (4.2%)d

12 (10.2%)

L/L

1 (0.8%)

2 (0.8%)

1 (0.8%)

  1. a p = 0.042, 95% CI of odd ratio: 0.37-0.98 for Burmese vs Karen (Chi-square test)
  2. b p = 0.021, 95% CI of odd ratio: 0.10-0.88 for Thai vs Burmese (Chi-square test)
  3. c p = 0.015, 95% CI of odd ratio: 1.15-4.45 for Burmese vs Karen (Chi-square test)
  4. d p = 0.026, 95% CI of odd ratio: 0.16-0.92 for Burmese vs Karen (Chi-square test)