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Table 2 Six TNF alleles polymorphism (TNF P-A, TNF P-B, TNF P-C, TNF P-D, TNF P-E, TNF P-F) based on five SNPs of biallelic polymorphism sites (-238, -308, -857, -863, -1031) in patients with severe (SM), uncomplicated falciparum (UM) and vivax malaria (VM) cases when data were combined for the three ethnic groups

From: Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity

TNF type

Polymorphic sites of the promoter region of TNF-α gene

SM

UM

VM

 

-238

-308

-857

-863

-1031

(%)

(%)

(%)

TNFP-A

G

G

C

C

T

41.3

52.3

53.5

TNFP-B

G

G

C

A

C

39.7

33.8

33.8

TNFP-C

A

G

C

C

C

3.2

3.3

4.2

TNFP-D

G

G

T

C

T

6.3

4.3

3.5

TNFP-E

G

A

C

C

T

7.9

5.0

3.5

TNFP-F

G

G

C

A

T

1.6

1.3

1.4