Table 2 Whole blood concentrations of mefloquine on Day-0 (pre-treatment), days 7, 14, 21, 28, 35 and 42 of treatment in patients with sensitive response and recrudescence.
Day of treatment | Sensitive response | Recrudescence response | ||
|---|---|---|---|---|
| Â | N | Mean (95%CI)* or Median (95% CI)** | N | Mean (95%CI)* or Median (95% CI)** |
Day 0** | 90 | 0 (0-1,714) | 36 | 0 (0-92) |
Day 1* | 36 | 1,411 (1,216-1,605) | 12 | 1,345 (1,067-1,624) |
Day 7* | 22 | 1,055 (806-1,304) | 9 | 754 (541-968) |
Day 14* | 21 | 659 (426-893) | 10 | 421 (181-660) |
Day 21* | 15 | 416 (258-575) | 11 | 359 (230-488) |
Day 28* | 13 | 233 (158-307) | 8 | 288 (146-329) |
Day 35* | 12 | 145 (96-195) | 6 | 179 (41-317) |
Day 42** | 19 | 19 (5-163) | 9 | 13 (0-49) |