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Table 2 Best fitted distributions, Akaike Information Criterion (AICs), and estimated median ages (IQR) for each severe outcome and each cell of the transmission intensity-seasonality matrix

From: The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings

Transmission Matrix category

Cerebral malaria

Severe Malarial Anaemia

Respiratory Distress

 

Best fitted model

AIC

Median age (IQR)

Best fitted model

AIC

Median age (IQR)

Best fitted model

AIC

Median age (IQR)

Marked Seasonality:

EIR < 10 pppy

Log-Logistic

13272

49 (31-72)

Log-Logistic

14146

27 (16-44)

Log-Logistic

7501

34 (19-57)

EIR 10-100 pppy

Gamma

4420

42 (25-64)

Log-Logistic

4799

25 (15-40)

Log-Normal

1161

36 (20-61)Ω

EIR > 100 pppy

Log-Normal

497

34 (19-57)

Weibull

259

30 (15-52)

-

-

-

No marked seasonality

EIR < 10 pppy

Log-Normal

672

41 (26-63)

-

-

-

-

-

-

EIR 10-100 pppy

Log-Logistic

20714

29 (18-47)

Log-Normal

47782

17 (10-29)

Log-Normal

20334

21 (12-36)

EIR > 100 pppy

-

-

-

Log-Logistic

3697

15 (9-25)

Log-Normal

523

23 (15-37)¥

  1. Same median age (IQR) results were obtained in the sensitivity analyses except when otherwise indicated
  2. ΩMedian age (IQR) obtained from sensitivity analyses: 36 (20-62)
  3. ¥Median age (IQR) obtained from sensitivity analyses: 22 (13-36)