Schematic representation of pftramp , pvtramp and pktramp. The figure shows the localization of the genes encoding PfTRAMP, PkTRAMP (both in gray) and PvTRAMP (in black) in P. falciparum, P. knowlesi and P. vivax chromosomic fragments, respectively, as well as the localization of the adjacent genes evaluated in this study. The arrows above each box indicate the ORF orientation, while the boxes show distribution and organization of the exons along the chromosomal segments. Genes are assigned according to their annotation in PlasmoDB. These chromosomic fragments comprised 21.5 kbp from the P. falciparum chromosome 12 (695,001-716,500 pb), 23.5 kbp from the P. vivax contig CM000455 (1,519,501-1,543,000 pb) and 24 kbp from the P. knowlesi chromosome 14 (1,548,001-1,572,000 pb).