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Table 2 Sensitivities of RDTs at different parasite densities

From: Performance of three multi-species rapid diagnostic tests for diagnosis of Plasmodium falciparum and Plasmodium vivax malaria in Oromia Regional State, Ethiopia

   CareStart ParaScreen ICT Combo McNemar p value1
P. falciparum        
Parasite density N Sensitivity: Pf or Pf+pan2 (95% CI3) CS-PS CS-ICT ICT-PS
< 200 p/μl 63 66.7% (53.7-78.1) 66.7% (53.7-78.1) 66.7% (53.7-78.1) 1.0 1.0 1.0
< 500 p/μl 90 70.0% (59.4-79.2) 70.0% (59.4-79.2) 70.0% (59.4-79.2) 1.0 1.0 1.0
< 5000 p/μl 188 79.1% (72.6-84.7) 79.1% (72.6-84.7) 79.1% (72.6-84.7) 1.0 1.0 1.0
> 5000 p/μl 118 95.8% (90.4-98.6) 95.7% (90.4-98.6) 95.7% (90.4-98.6) 1.0 1.0 1.0
P. vivax        
Parasite density N Sensitivity: pan band only4 (95% CI) CS-PS CS-ICT ICT-PS
< 200 p/μl 9 77.8% (40.0-97.2) 88.9% (51.8-99.7) 66.7% (29.9-92.5) 0.32 0.56 0.16
< 500 p/μl 28 82.1% (63.1-93.9) 89.3% (71.8-97.7) 85.7% (67.3-96.0) 0.32 0.65 0.56
< 5000 p/μl 116 82.8% (74.6-89.1) 82.8% (74.6-89.1) 82.8% (74.6-89.1) 1.0 1.0 1.0
> 5000 p/μl 128 86.7% (79.6-92.1) 82.8% (75.1-88.9) 86.7% (79.6-92.1) 0.03 1.0 0.03
  1. 1 Significant relationships (p > 0.05) in bold type.
  2. 2 RDT result showed either P. falciparum HRP2 band only, or HRP2 band and pan pLDH band. Individuals with P. vivax infection only excluded.
  3. 3 95% Confidence Interval
  4. 4 RDT result showing pan band only. Individuals with any P. falciparum infection excluded.