Figure 1From: Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytesThe structure and characteristics of PFD1235w. (A) Domain structure of PFD1235w with amino acid domain boundaries indicated. Recombinant PFD1235w protein domains produced in (B) baculovirus-infected insect cells (solid lines) and (C) E. coli (dotted lines). (D) Purity (%), (E) yield (mg/ml), (F) table of theoretical and observed molecular weight in kDa of insect cell and E. coli produced domains. Lines ending with a diamond in (B) and (C) indicates recombinant protein inducing IE surface reactive antibodies in rats and (*) constructs tested by Luminex. NM: not measured, NA: not applicable, NP: not produced.Back to article page