Figure 1

Plasma from acute malaria inhibits ³H-hypoxanthine uptake by Plasmodium falciparum. Parasites were incubated in malaria culture medium with 10% (v/v) 'immune' plasma containing anti-malarial antibodies for 48 hours. Parasite uptake of hypoxanthine (in counts per minute; cpm) is shown as the median values with 25^th and 75^th percentiles and ranges from 4 experiments in duplicate. Control parasites were incubated in culture medium with 10% plasma from healthy donors. ^*p ≤ 0.05 (Mann-Whitney U test).