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Table 1 Correlation of in vitro responses of 23 strains of Plasmodium falciparum to pyronaridine (PND), and artesunate (AS), chloroquine (CQ), quinine (QN), mefloquine (MQ), monodesethylamodiaquine (MDAQ), lumefantrine (LMF), atovaquone (ATV), pyrimethamine (PY) and doxycycline (DOX)

From: Absence of association between pyronaridine in vitro responses and polymorphisms in genes involved in quinoline resistance in Plasmodium falciparum

Drug pair

r

r2

P-value

PND

AS

+ 0.4488

0.2014

0.0317

PND

ATV

+ 0.3758

0.1412

0.0772

PND

PY

+ 0.2116

0.0448

0.3323

PND

QN

+ 0.2035

0.0414

0.3516

PND

MQ

- 0.3124

0.1050

0.1468

PND

DOX

- 0.1782

0.0318

0.4159

PND

LMF

- 0.1412

0.0199

0.5205

PND

MDAQ

- 0.1050

0.0110

0.6335

PND

CQ

- 0.0548

0.0030

0.8040