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Figure 3 | Malaria Journal

Figure 3

From: Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy

Figure 3

Prevalence of anti-malarial drug resistance markers in Cameroon. T represents the threonine (T) mutation on codon 76 (76T) of the Pfcrt gene. Y represents tyrosine (Y) mutation at codon 86 (86Y) of the Pfmdr1 gene as putative markers for Amodiaquine failure (AQF (D28)). Sulphadoxine-pyrimethamine failure (SPF (D28)) whose molecular markers, IRN represents the isoleucine, arginine and asparagine mutations at codons 51, 59 and 108 (IRN) of the dhfr gene and SGK represents the serine, glycine and lysine mutations at codon 436, 437 and 540 of the dhps gene:

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