Figure 2

Phosphatidylserine (PS) exposure in pRBC and nRBC during P. yoelii 17XL infection. Balb/c mice (n = 5) were infected with 10⁶ P. yoelii 17XL-pRBC and, than, PS exposure was evaluated in the late stage of infection by flow cytometry using Syto 16 (FL-1) and annexin V-PE (FL-2) dual staining. In parallel, non-infected, age-matched mice were used as control (n = 4). (A) Representative flow cytometry analysis of pRBC exposing PS in infected mice. (B) Representative flow cytometry analysis of nRBC exposing PS in infected and non-infected mice. (C) Means ± SEM of levels of nRBC exposing PS in infected and non-infected mice detected ex-vivo and after 24 h culture. Data are representative of three separate experiments.